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USP1 deubiquitinase: cellular functions, regulatory mechanisms and emerging potential as target in cancer therapy
Reversible protein ubiquitination is emerging as a key process for maintaining cell homeostasis, and the enzymes that participate in this process, in particular E3 ubiquitin ligases and deubiquitinases (DUBs), are increasingly being regarded as candidates for drug discovery. Human DUBs are a group o...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750636/ https://www.ncbi.nlm.nih.gov/pubmed/23937906 http://dx.doi.org/10.1186/1476-4598-12-91 |