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Mitochondrial respiratory chain dysfunction modulates metalloproteases -1, -3 and -13 in human normal chondrocytes in culture

BACKGROUND: Mitochondrion has an important role in the osteoarthritis (OA) pathology. We have previously demonstrated that the alteration of the mitochondrial respiratory chain (MRC) contributes to the inflammatory response of the chondrocyte. However its implication in the process of cartilage dest...

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Detalles Bibliográficos
Autores principales: Cillero-Pastor, Berta, Rego-Pérez, Ignacio, Oreiro, Natividad, Fernandez-Lopez, Carlos, Blanco, Francisco J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750811/
https://www.ncbi.nlm.nih.gov/pubmed/23937653
http://dx.doi.org/10.1186/1471-2474-14-235