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Mitochondrial respiratory chain dysfunction modulates metalloproteases -1, -3 and -13 in human normal chondrocytes in culture
BACKGROUND: Mitochondrion has an important role in the osteoarthritis (OA) pathology. We have previously demonstrated that the alteration of the mitochondrial respiratory chain (MRC) contributes to the inflammatory response of the chondrocyte. However its implication in the process of cartilage dest...
Autores principales: | Cillero-Pastor, Berta, Rego-Pérez, Ignacio, Oreiro, Natividad, Fernandez-Lopez, Carlos, Blanco, Francisco J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750811/ https://www.ncbi.nlm.nih.gov/pubmed/23937653 http://dx.doi.org/10.1186/1471-2474-14-235 |
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