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Engineered Pichia pastoris for enhanced production of S-adenosylmethionine

A genetically engineered strain of Pichia pastoris expressing S-adenosylmethionine synthetase gene from Saccharomyces cerevisiae under the control of AOX 1 promoter was developed. Induction of recombinant strain with 1% methanol resulted in the expression of SAM2 protein of ~ 42 kDa, whereas control...

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Detalles Bibliográficos
Autores principales: Kamarthapu, Venu, Ragampeta, Srinivas, Rao, Khareedu Venkateswara, Reddy, Vudem Dashavantha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750815/
https://www.ncbi.nlm.nih.gov/pubmed/23890127
http://dx.doi.org/10.1186/2191-0855-3-40