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In situ magnetic separation of antibody fragments from Escherichia coli in complex media
BACKGROUND: In situ magnetic separation (ISMS) has emerged as a powerful tool to overcome process constraints such as product degradation or inhibition of target production. In the present work, an integrated ISMS process was established for the production of his-tagged single chain fragment variabl...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750846/ https://www.ncbi.nlm.nih.gov/pubmed/23688064 http://dx.doi.org/10.1186/1472-6750-13-44 |