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Broad-spectrum antiviral activity of chebulagic acid and punicalagin against viruses that use glycosaminoglycans for entry

BACKGROUND: We previously identified two hydrolyzable tannins, chebulagic acid (CHLA) and punicalagin (PUG) that blocked herpes simplex virus type 1 (HSV-1) entry and spread. These compounds inhibited viral glycoprotein interactions with cell surface glycosaminoglycans (GAGs). Based on this property...

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Detalles Bibliográficos
Autores principales: Lin, Liang-Tzung, Chen, Ting-Ying, Lin, Song-Chow, Chung, Chueh-Yao, Lin, Ta-Chen, Wang, Guey-Horng, Anderson, Robert, Lin, Chun-Ching, Richardson, Christopher D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750913/
https://www.ncbi.nlm.nih.gov/pubmed/23924316
http://dx.doi.org/10.1186/1471-2180-13-187