Pharmacokinetics and thrombolytic effects of the recombinant tissue-type plasminogen activator in horses

BACKGROUND: To test the efficacy of the recombinant tissue-type plasminogen activator (rt-PA) alteplase in horses, the thrombolytic effect was tested in in vitro generated equine thrombi. The extent of lysis was determined by measuring the decrease in thrombi weight over a period of 4 hours. In vivo...

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Detalles Bibliográficos
Autores principales: Bäumer, Wolfgang, Herrling, Gudrun M, Feige, Karsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750949/
https://www.ncbi.nlm.nih.gov/pubmed/23938183
http://dx.doi.org/10.1186/1746-6148-9-158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750949/
https://www.ncbi.nlm.nih.gov/pubmed/23938183
http://dx.doi.org/10.1186/1746-6148-9-158

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