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Viral protein R of human immunodeficiency virus type-1 induces retrotransposition of long interspersed element-1

BACKGROUND: Viral protein R (Vpr), a protein of human immunodeficiency virus type-1 (HIV-1) with various biological functions, was shown to be present in the blood of HIV-1-positive patients. However, it remained unclear whether circulating Vpr in patients’ blood is biologically active. Here, we exa...

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Detalles Bibliográficos
Autores principales: Iijima, Kenta, Okudaira, Noriyuki, Tamura, Masato, Doi, Akihiro, Saito, Yoshikazu, Shimura, Mari, Goto, Motohito, Matsunaga, Akihiro, Kawamura, Yuki I, Otsubo, Takeshi, Dohi, Taeko, Hoshino, Shigeki, Kano, Shigeyuki, Hagiwara, Shotaro, Tanuma, Junko, Gatanaga, Hiroyuki, Baba, Masanori, Iguchi, Taku, Yanagita, Motoko, Oka, Shinichi, Okamura, Tadashi, Ishizaka, Yukihito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751050/
https://www.ncbi.nlm.nih.gov/pubmed/23915234
http://dx.doi.org/10.1186/1742-4690-10-83