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A simple methodology to assess endolysosomal protease activity involved in antigen processing in human primary cells

BACKGROUND: Endolysosomes play a key role in maintaining the homeostasis of the cell. They are made of a complex set of proteins that degrade lipids, proteins and sugars. Studies involving endolysosome contribution to cellular functions such as MHC class I and II epitope production have used recombi...

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Detalles Bibliográficos
Autores principales: Vaithilingam, Archana, Lai, Nicole Y, Duong, Ellen, Boucau, Julie, Xu, Yang, Shimada, Mariko, Gandhi, Malini, Le Gall, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751085/
https://www.ncbi.nlm.nih.gov/pubmed/23937268
http://dx.doi.org/10.1186/1471-2121-14-35