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A simple methodology to assess endolysosomal protease activity involved in antigen processing in human primary cells
BACKGROUND: Endolysosomes play a key role in maintaining the homeostasis of the cell. They are made of a complex set of proteins that degrade lipids, proteins and sugars. Studies involving endolysosome contribution to cellular functions such as MHC class I and II epitope production have used recombi...
Autores principales: | Vaithilingam, Archana, Lai, Nicole Y, Duong, Ellen, Boucau, Julie, Xu, Yang, Shimada, Mariko, Gandhi, Malini, Le Gall, Sylvie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751085/ https://www.ncbi.nlm.nih.gov/pubmed/23937268 http://dx.doi.org/10.1186/1471-2121-14-35 |
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