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Boron neutron capture therapy induces cell cycle arrest and cell apoptosis of glioma stem/progenitor cells in vitro

BACKGROUND: Glioma stem cells in the quiescent state are resistant to clinical radiation therapy. An almost inevitable glioma recurrence is due to the persistence of these cells. The high linear energy transfer associated with boron neutron capture therapy (BNCT) could kill quiescent and proliferati...

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Detalles Bibliográficos
Autores principales: Sun, Ting, Zhang, Zizhu, Li, Bin, Chen, Guilin, Xie, Xueshun, Wei, Yongxin, Wu, Jie, Zhou, Youxin, Du, Ziwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751121/
https://www.ncbi.nlm.nih.gov/pubmed/23915425
http://dx.doi.org/10.1186/1748-717X-8-195