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The cost of antibiotic resistance depends on evolutionary history in Escherichia coli

BACKGROUND: The persistence of antibiotic resistance depends on the fitness effects of resistance elements in the absence of antibiotics. Recent work shows that the fitness effect of a given resistance mutation is influenced by other resistance mutations on the same genome. However, resistant bacter...

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Detalles Bibliográficos
Autores principales: Angst, Daniel C, Hall, Alex R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751127/
https://www.ncbi.nlm.nih.gov/pubmed/23914906
http://dx.doi.org/10.1186/1471-2148-13-163