Cell-cycle synchronization reverses Taxol resistance of human ovarian cancer cell lines

BACKGROUND: Taxol is a powerful chemotherapy agent leading to mitotic arrest and cell death; however, its clinical efficacy has been hampered due to the development of drug resistance. Taxol specifically targets the cell cycle. Progress through mitosis (M stage) is an absolute requirement for drug-i...

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Detalles Bibliográficos
Autores principales: Wang, Xueqing, Pan, Lingya, Mao, Ning, Sun, Lifang, Qin, Xiangjuan, Yin, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751242/
https://www.ncbi.nlm.nih.gov/pubmed/23899403
http://dx.doi.org/10.1186/1475-2867-13-77

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751242/
https://www.ncbi.nlm.nih.gov/pubmed/23899403
http://dx.doi.org/10.1186/1475-2867-13-77

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