Cargando…
Cell-cycle synchronization reverses Taxol resistance of human ovarian cancer cell lines
BACKGROUND: Taxol is a powerful chemotherapy agent leading to mitotic arrest and cell death; however, its clinical efficacy has been hampered due to the development of drug resistance. Taxol specifically targets the cell cycle. Progress through mitosis (M stage) is an absolute requirement for drug-i...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751242/ https://www.ncbi.nlm.nih.gov/pubmed/23899403 http://dx.doi.org/10.1186/1475-2867-13-77 |