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DNA vaccines targeting the encoded antigens to dendritic cells induce potent antitumor immunity in mice

BACKGROUND: Although DNA vaccine holds a great potential for cancer immunotherapy, effective long-lasting antitumoral immunity sufficient to induce durable responses in cancer patients remains to be achieved. Considering the pivotal role of dendritic cells (DC) in the antigen processing and presenta...

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Detalles Bibliográficos
Autores principales: Cao, Jun, Jin, Yiqi, Li, Wei, Zhang, Bin, He, Yang, Liu, Hongqiang, Xia, Ning, Wei, Huafeng, Yan, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751307/
https://www.ncbi.nlm.nih.gov/pubmed/23941509
http://dx.doi.org/10.1186/1471-2172-14-39