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Use of dexmedetomidine for prophylactic analgesia and sedation in delayed extubation patients after craniotomy: a study protocol and statistical analysis plan for a randomized controlled trial

BACKGROUND: Pain and agitation are common in patients after craniotomy. They can result in tachycardia, hypertension, immunosuppression, increased catecholamine production and increased oxygen consumption. Dexmedetomidine, an alpha-2 agonist, provides adequate sedation without respiratory depression...

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Detalles Bibliográficos
Autores principales: Zhao, Li-Hong, Shi, Zhong-Hua, Yin, Ning-Ning, Zhou, Jian-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751309/
https://www.ncbi.nlm.nih.gov/pubmed/23941549
http://dx.doi.org/10.1186/1745-6215-14-251