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Use of dexmedetomidine for prophylactic analgesia and sedation in delayed extubation patients after craniotomy: a study protocol and statistical analysis plan for a randomized controlled trial
BACKGROUND: Pain and agitation are common in patients after craniotomy. They can result in tachycardia, hypertension, immunosuppression, increased catecholamine production and increased oxygen consumption. Dexmedetomidine, an alpha-2 agonist, provides adequate sedation without respiratory depression...
Autores principales: | Zhao, Li-Hong, Shi, Zhong-Hua, Yin, Ning-Ning, Zhou, Jian-Xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751309/ https://www.ncbi.nlm.nih.gov/pubmed/23941549 http://dx.doi.org/10.1186/1745-6215-14-251 |
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