Role of hypoxia inducible factor-1 in keratinocyte inflammatory response and neutrophil recruitment

BACKGROUND: Hypoxia inducible factor-1 (HIF-1) is a major regulator of the cellular adaption to low oxygen stress and the innate immune function of myeloid cells. Treatment with the novel HIF-1 stabilizing drug AKB-4924 has been shown to enhance the bactericidal activity of keratinocytes as well as...

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Detalles Bibliográficos
Autores principales: Leire, Emma, Olson, Josh, Isaacs, Hart, Nizet, Victor, Hollands, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751314/
https://www.ncbi.nlm.nih.gov/pubmed/23937964
http://dx.doi.org/10.1186/1476-9255-10-28

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751314/
https://www.ncbi.nlm.nih.gov/pubmed/23937964
http://dx.doi.org/10.1186/1476-9255-10-28

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