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Contribution of quantitative changes in individual ionic current systems to the embryonic development of ventricular myocytes: a simulation study

Early embryonic rodent ventricular cells exhibit spontaneous action potential (AP), which disappears in later developmental stages. Here, we used 3 mathematical models—the Kyoto, Ten Tusscher–Panfilov, and Luo–Rudy models—to present an overview of the functional landscape of developmental changes in...

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Detalles Bibliográficos
Autores principales: Okubo, Chikako, Sano, Hitomi I., Naito, Yasuhiro, Tomita, Masaru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751412/
https://www.ncbi.nlm.nih.gov/pubmed/23760774
http://dx.doi.org/10.1007/s12576-013-0271-x