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Transcriptional profiling reveals progeroid Ercc1(-/Δ) mice as a model system for glomerular aging

BACKGROUND: Aging-related kidney diseases are a major health concern. Currently, models to study renal aging are lacking. Due to a reduced life-span progeroid models hold the promise to facilitate aging studies and allow examination of tissue-specific changes. Defects in genome maintenance in the Er...

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Detalles Bibliográficos
Autores principales: Schermer, Bernhard, Bartels, Valerie, Frommolt, Peter, Habermann, Bianca, Braun, Fabian, Schultze, Joachim L, Roodbergen, Marianne, Hoeijmakers, Jan HJ, Schumacher, Björn, Nürnberg, Peter, Dollé, Martijn ET, Benzing, Thomas, Müller, Roman-Ulrich, Kurschat, Christine E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751413/
https://www.ncbi.nlm.nih.gov/pubmed/23947592
http://dx.doi.org/10.1186/1471-2164-14-559