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Transcriptional profiling reveals progeroid Ercc1(-/Δ) mice as a model system for glomerular aging
BACKGROUND: Aging-related kidney diseases are a major health concern. Currently, models to study renal aging are lacking. Due to a reduced life-span progeroid models hold the promise to facilitate aging studies and allow examination of tissue-specific changes. Defects in genome maintenance in the Er...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751413/ https://www.ncbi.nlm.nih.gov/pubmed/23947592 http://dx.doi.org/10.1186/1471-2164-14-559 |