Identification of somatic mutations in cancer through Bayesian-based analysis of sequenced genome pairs

BACKGROUND: The field of cancer genomics has rapidly adopted next-generation sequencing (NGS) in order to study and characterize malignant tumors with unprecedented resolution. In particular for cancer, one is often trying to identify somatic mutations – changes specific to a tumor and not within an...

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Detalles Bibliográficos
Autores principales: Christoforides, Alexis, Carpten, John D, Weiss, Glen J, Demeure, Michael J, Von Hoff, Daniel D, Craig, David W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751438/
https://www.ncbi.nlm.nih.gov/pubmed/23642077
http://dx.doi.org/10.1186/1471-2164-14-302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751438/
https://www.ncbi.nlm.nih.gov/pubmed/23642077
http://dx.doi.org/10.1186/1471-2164-14-302

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