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Identification of somatic mutations in cancer through Bayesian-based analysis of sequenced genome pairs

BACKGROUND: The field of cancer genomics has rapidly adopted next-generation sequencing (NGS) in order to study and characterize malignant tumors with unprecedented resolution. In particular for cancer, one is often trying to identify somatic mutations – changes specific to a tumor and not within an...

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Detalles Bibliográficos
Autores principales:	Christoforides, Alexis, Carpten, John D, Weiss, Glen J, Demeure, Michael J, Von Hoff, Daniel D, Craig, David W
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751438/ https://www.ncbi.nlm.nih.gov/pubmed/23642077 http://dx.doi.org/10.1186/1471-2164-14-302

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