Design of multiligand inhibitors for the swine flu H1N1 neuraminidase binding site

Viral neuraminidase inhibitors such as oseltamivir and zanamivir prevent early virus multiplication by blocking sialic acid cleavage on host cells. These drugs are effective for the treatment of a variety of influenza subtypes, including swine flu (H1N1). The binding site for these drugs is well est...

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Detalles Bibliográficos
Autores principales: Narayanan, Manoj M, Nair, Chandrasekhar B, Sanjeeva, Shilpa K, Rao, PV Subba, Pullela, Phani K, Barrow, Colin J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751451/
https://www.ncbi.nlm.nih.gov/pubmed/23983477
http://dx.doi.org/10.2147/AABC.S49503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751451/
https://www.ncbi.nlm.nih.gov/pubmed/23983477
http://dx.doi.org/10.2147/AABC.S49503

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