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Stability properties of PrP(Sc) from cattle with experimental transmissible spongiform encephalopathies: use of a rapid whole homogenate, protease-free assay

BACKGROUND: Transmissible Spongiform Encephalopathies (TSEs), including scrapie in sheep, chronic wasting disease (CWD) in cervids, transmissible mink encephalopathy (TME), and bovine spongiform encephalopathy (BSE), are fatal diseases of the nervous system associated with accumulation of misfolded...

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Detalles Bibliográficos
Autores principales: Vrentas, Catherine E, Greenlee, Justin J, Baron, Thierry, Caramelli, Maria, Czub, Stefanie, Nicholson, Eric M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751458/
https://www.ncbi.nlm.nih.gov/pubmed/23945217
http://dx.doi.org/10.1186/1746-6148-9-167