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Intrastriatal injections of KN-93 ameliorates levodopa-induced dyskinesia in a rat model of Parkinson’s disease

BACKGROUND: Levodopa remains the most effective drug for the treatment of Parkinson’s disease (PD). However, long-term levodopa treatment is associated with the emergence of levodopa-induced dyskinesia (LID), which has hampered its use for PD treatment. The mechanisms of LID are only partially under...

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Detalles Bibliográficos
Autores principales: Yang, Xinxin, Wu, Na, Song, Lu, Liu, Zhenguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751461/
https://www.ncbi.nlm.nih.gov/pubmed/23983471
http://dx.doi.org/10.2147/NDT.S45422