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Oral antigen exposure in extreme early life in lambs influences the magnitude of the immune response which can be generated in later life
BACKGROUND: Previous investigations in newborn lambs determined that adenovirus-mediated expression of antigen to a localized region of the gut induced antigen-specific mucosal and systemic immunity. These experiments were limited in that the localized region of the gut to which antigen was introduc...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751536/ https://www.ncbi.nlm.nih.gov/pubmed/23937675 http://dx.doi.org/10.1186/1746-6148-9-160 |