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Identification of novel key amino acids at the interface of the transmembrane domains of human BST-2 and HIV-1 Vpu
BACKGROUND: BST-2 (bone marrow stromal cell antigen 2) is an interferon-inducible protein that inhibits virus release by tethering viral particles to the cell surface. This antiviral activity of BST-2 is antagonized by HIV-1 accessory protein Vpu. Vpu physically interacts with BST-2 through their mu...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751551/ https://www.ncbi.nlm.nih.gov/pubmed/23919512 http://dx.doi.org/10.1186/1742-4690-10-84 |