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Identification of novel key amino acids at the interface of the transmembrane domains of human BST-2 and HIV-1 Vpu

BACKGROUND: BST-2 (bone marrow stromal cell antigen 2) is an interferon-inducible protein that inhibits virus release by tethering viral particles to the cell surface. This antiviral activity of BST-2 is antagonized by HIV-1 accessory protein Vpu. Vpu physically interacts with BST-2 through their mu...

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Detalles Bibliográficos
Autores principales:	Pang, Xiaojing, Hu, Siqi, Li, Jian, Xu, Fengwen, Mei, Shan, Zhou, Jinming, Cen, Shan, Jin, Qi, Guo, Fei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751551/ https://www.ncbi.nlm.nih.gov/pubmed/23919512 http://dx.doi.org/10.1186/1742-4690-10-84

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