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Polyunsaturated fatty acid relatively decreases cholesterol content in THP-1 macrophage-derived foam cell: partly correlates with expression profile of CIDE and PAT members

BACKGROUND: Polyunsaturated fatty acids (PUFAs) have positive effect on the regulation of plasma lipids. But the mechanism for them to modulate lipid homeostasis in macrophage is still unclear. In this study, we employed PUFA to pretreat macrophages and evaluated the variations of lipid droplet (LD)...

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Detalles Bibliográficos
Autores principales: Song, Yue, Zhang, Li-Jun, Li, Hang, Gu, Yu, Li, Fan-Fan, Jiang, Li-Na, Liu, Fang, Ye, Jing, Li, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751560/
https://www.ncbi.nlm.nih.gov/pubmed/23879935
http://dx.doi.org/10.1186/1476-511X-12-111