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Stability of genomic imprinting in human induced pluripotent stem cells

BACKGROUND: hiPSCs are generated through epigenetic reprogramming of somatic tissue. Genomic imprinting is an epigenetic phenomenon through which monoallelic gene expression is regulated in a parent-of-origin-specific manner. Reprogramming relies on the successful erasure of marks of differentiation...

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Detalles Bibliográficos
Autores principales: Hiura, Hitoshi, Toyoda, Masashi, Okae, Hiroaki, Sakurai, Masahiro, Miyauchi, Naoko, Sato, Akiko, Kiyokawa, Nobutaka, Okita, Hajime, Miyagawa, Yoshitaka, Akutsu, Hidenori, Nishino, Koichiro, Umezawa, Akihiro, Arima, Takahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751563/
https://www.ncbi.nlm.nih.gov/pubmed/23631808
http://dx.doi.org/10.1186/1471-2156-14-32