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Modulation of the oscillatory mechanics of lung tissue and the oxidative stress response induced by arginase inhibition in a chronic allergic inflammation model

BACKGROUND: The importance of the lung parenchyma in the pathophysiology of asthma has previously been demonstrated. Considering that nitric oxide synthases (NOS) and arginases compete for the same substrate, it is worthwhile to elucidate the effects of complex NOS-arginase dysfunction in the pathop...

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Detalles Bibliográficos
Autores principales: Aristoteles, Luciana RCRB, Righetti, Renato F, Pinheiro, Nathalia Montouro, Franco, Rosana B, Starling, Claudia M, da Silva, Julie CP, Pigati, Patrícia Angeli, Caperuto, Luciana C, Prado, Carla M, Dolhnikoff, Marisa, Martins, Milton A, Leick, Edna A, Tibério, Iolanda FLC
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751598/
https://www.ncbi.nlm.nih.gov/pubmed/23947680
http://dx.doi.org/10.1186/1471-2466-13-52