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Mena/VASP and αII-Spectrin complexes regulate cytoplasmic actin networks in cardiomyocytes and protect from conduction abnormalities and dilated cardiomyopathy

BACKGROUND: In the heart, cytoplasmic actin networks are thought to have important roles in mechanical support, myofibrillogenesis, and ion channel function. However, subcellular localization of cytoplasmic actin isoforms and proteins involved in the modulation of the cytoplasmic actin networks are...

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Detalles Bibliográficos
Autores principales: Benz, Peter M, Merkel, Carla J, Offner, Kristin, Abeßer, Marco, Ullrich, Melanie, Fischer, Tobias, Bayer, Barbara, Wagner, Helga, Gambaryan, Stepan, Ursitti, Jeanine A, Adham, Ibrahim M, Linke, Wolfgang A, Feller, Stephan M, Fleming, Ingrid, Renné, Thomas, Frantz, Stefan, Unger, Andreas, Schuh, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751641/
https://www.ncbi.nlm.nih.gov/pubmed/23937664
http://dx.doi.org/10.1186/1478-811X-11-56