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Nrf2 is required to maintain the self-renewal of glioma stem cells

BACKGROUND: Glioblastomas are deadly cancers that display a functional cellular hierarchy maintained by self-renewing glioma stem cells (GSCs). Self-renewal is a complex biological process necessary for maintaining the glioma stem cells. Nuclear factor rythroid 2-related factor 2(Nrf2) plays a signi...

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Detalles Bibliográficos
Autores principales: Zhu, Jianhong, Wang, Handong, Sun, Qing, Ji, Xiangjun, Zhu, Lin, Cong, Zixiang, Zhou, Yuan, Liu, Huandong, Zhou, Mengliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751732/
https://www.ncbi.nlm.nih.gov/pubmed/23937621
http://dx.doi.org/10.1186/1471-2407-13-380