Longitudinal transcriptomic dysregulation in the peripheral blood of transgenic Huntington’s disease monkeys

BACKGROUND: Huntington’s Disease (HD) is a progressive neurodegenerative disorder caused by an expansion in the polyglutamine (polyQ) region of the Huntingtin (HTT) gene. The clinical features of HD are characterized by cognitive, psychological, and motor deficits. Molecular instability, a core comp...

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Detalles Bibliográficos
Autores principales: Kocerha, Jannet, Liu, Yuhong, Willoughby, David, Chidamparam, Kumaravel, Benito, Joseph, Nelson, Kate, Xu, Yan, Chi, Tim, Engelhardt, Heidi, Moran, Sean, Yang, Shang-Hsun, Li, Shi-Hua, Li, Xiao-Jiang, Larkin, Katherine, Neumann, Adam, Banta, Heather, Yang, Jin Jing, Chan, Anthony WS
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751855/
https://www.ncbi.nlm.nih.gov/pubmed/23957861
http://dx.doi.org/10.1186/1471-2202-14-88

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751855/
https://www.ncbi.nlm.nih.gov/pubmed/23957861
http://dx.doi.org/10.1186/1471-2202-14-88

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