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Sister chromatid cohesion defects are associated with chromosome instability in Hodgkin lymphoma cells

BACKGROUND: Chromosome instability manifests as an abnormal chromosome complement and is a pathogenic event in cancer. Although a correlation between abnormal chromosome numbers and cancer exist, the underlying mechanisms that cause chromosome instability are poorly understood. Recent data suggests...

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Detalles Bibliográficos
Autores principales: Sajesh, Babu V, Lichtensztejn, Zelda, McManus, Kirk J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751861/
https://www.ncbi.nlm.nih.gov/pubmed/23962039
http://dx.doi.org/10.1186/1471-2407-13-391