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A Liposomal Drug Platform Overrides Peptide Ligand Targeting to a Cancer Biomarker, Irrespective of Ligand Affinity or Density

One method for improving cancer treatment is the use of nanoparticle drugs functionalized with targeting ligands that recognize receptors expressed selectively by tumor cells. In theory such targeting ligands should specifically deliver the nanoparticle drug to the tumor, increasing drug concentrati...

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Detalles Bibliográficos
Autores principales: Gray, Bethany Powell, McGuire, Michael J., Brown, Kathlynn C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751880/
https://www.ncbi.nlm.nih.gov/pubmed/24009717
http://dx.doi.org/10.1371/journal.pone.0072938