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Dysregulated methylation at imprinted genes in prostate tumor tissue detected by methylation microarray

BACKGROUND: Imprinting is an important epigenetic regulator of gene expression that is often disrupted in cancer. While loss of imprinting (LOI) has been reported for two genes in prostate cancer (IGF2 and TFPI2), disease-related changes in methylation across all imprinted gene regions has not been...

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Detalles Bibliográficos
Autores principales: Jacobs, Daniel I, Mao, Yingying, Fu, Alan, Kelly, William Kevin, Zhu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751920/
https://www.ncbi.nlm.nih.gov/pubmed/23890537
http://dx.doi.org/10.1186/1471-2490-13-37