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Dysregulated methylation at imprinted genes in prostate tumor tissue detected by methylation microarray
BACKGROUND: Imprinting is an important epigenetic regulator of gene expression that is often disrupted in cancer. While loss of imprinting (LOI) has been reported for two genes in prostate cancer (IGF2 and TFPI2), disease-related changes in methylation across all imprinted gene regions has not been...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751920/ https://www.ncbi.nlm.nih.gov/pubmed/23890537 http://dx.doi.org/10.1186/1471-2490-13-37 |