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Association Study of Polymorphisms in Selenoprotein Genes and Kashin–Beck Disease and Serum Selenium/Iodine Concentration in a Tibetan Population

BACKGROUND: Kashin-Beck disease is a kind of degenerative osteoarthropathy. Genetic factors may play an important role in the pathogenesis of KBD. OBJECTIVE: To investigate the association of the selenoprotein genes GPX1 (rs1050450, rs1800668, and rs3811699), TrxR2 (rs5748469), and DIO2 (rs225014) w...

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Detalles Bibliográficos
Autores principales: Huang, Lulin, Shi, Yi, Lu, Fang, Zheng, Hong, Liu, Xiaoqi, Gong, Bo, Yang, Jiyun, Lin, Ying, Cheng, Jing, Ma, Shi, Lin, He, Yang, Zhenglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751926/
https://www.ncbi.nlm.nih.gov/pubmed/24058403
http://dx.doi.org/10.1371/journal.pone.0071411