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Piwi Genes Are Dispensable for Normal Hematopoiesis in Mice

Hematopoietic stem cells (HSC) must engage in a life-long balance between self-renewal and differentiation to sustain hematopoiesis. The highly conserved PIWI protein family regulates proliferative states of stem cells and their progeny in diverse organisms. A Human piwi gene (for clarity, the non-i...

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Detalles Bibliográficos
Autores principales: Nolde, Mona J., Cheng, Ee-chun, Guo, Shangqin, Lin, Haifan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751959/
https://www.ncbi.nlm.nih.gov/pubmed/24058407
http://dx.doi.org/10.1371/journal.pone.0071950