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A Switch III Motif Relays Signaling between a B(12) Enzyme and its G-protein Chaperone()

Fidelity during cofactor assembly is essential for the proper functioning of metalloenzymes and is ensured by specific chaperones. MeaB, a G-protein chaperone for the coenzyme B(12)-dependent radical enzyme, methylmalonyl-CoA mutase (MCM), utilizes the energy of GTP binding and/or hydrolysis to regu...

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Detalles Bibliográficos
Autores principales: Lofgren, Michael, Padovani, Dominique, Koutmos, Markos, Banerjee, Ruma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3752380/
https://www.ncbi.nlm.nih.gov/pubmed/23873214
http://dx.doi.org/10.1038/nchembio.1298