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A Switch III Motif Relays Signaling between a B(12) Enzyme and its G-protein Chaperone()
Fidelity during cofactor assembly is essential for the proper functioning of metalloenzymes and is ensured by specific chaperones. MeaB, a G-protein chaperone for the coenzyme B(12)-dependent radical enzyme, methylmalonyl-CoA mutase (MCM), utilizes the energy of GTP binding and/or hydrolysis to regu...
Autores principales: | Lofgren, Michael, Padovani, Dominique, Koutmos, Markos, Banerjee, Ruma |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3752380/ https://www.ncbi.nlm.nih.gov/pubmed/23873214 http://dx.doi.org/10.1038/nchembio.1298 |
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