Increased apical Na(+) permeability in cystic fibrosis is supported by a quantitative model of epithelial ion transport

Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, which encodes an anion channel. In the human lung CFTR loss causes abnormal ion transport across airway epithelial cells. As a result CF individuals produce thick mucus, suffer persist...

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Detalles Bibliográficos
Autores principales: O’Donoghue, Donal L, Dua, Vivek, Moss, Guy W J, Vergani, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Science Inc 2013
Materias:
Computational Physiology and Modelling
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3752450/
https://www.ncbi.nlm.nih.gov/pubmed/23732645
http://dx.doi.org/10.1113/jphysiol.2013.253955

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3752450/
https://www.ncbi.nlm.nih.gov/pubmed/23732645
http://dx.doi.org/10.1113/jphysiol.2013.253955

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