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Association between hTERT rs2736100 polymorphism and sensitivity to anti-cancer agents

Background: The rs2736100 single nucleotide polymorphism (SNP) is located in the intron 2 of human telomerase reverse transcriptase (hTERT) gene. Recent genome-wide association studies (GWAS) have consistently supported the strong association between this SNP and risk for multiple cancers. Given the...

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Detalles Bibliográficos
Autores principales: Kim, Julie, Jones-Hall, Yava L., Wei, Rongrong, Myers, Jamie, Qi, Yuan, Knipp, Gregory T., Liu, Wanqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3752523/
https://www.ncbi.nlm.nih.gov/pubmed/23986774
http://dx.doi.org/10.3389/fgene.2013.00162