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Formation of lipid raft redox signalling platforms in glomerular endothelial cells: an early event of homocysteine-induced glomerular injury

The present study tested the hypothesis that homocysteine (Hcys)-induced ceramide production stimulates lipid rafts (LRs) clustering on the membrane of glomerular endothelial cells (GECs) to form redox signalling platforms by aggregation and activation of NADPH oxidase subunits and thereby enhances...

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Detalles Bibliográficos
Autores principales: Yi, Fan, Jin, Si, Zhang, Fan, Xia, Min, Bao, Jun-Xiang, Hu, Junjun, Poklis, Justin L, Li, Pin-Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3752605/
https://www.ncbi.nlm.nih.gov/pubmed/20196779
http://dx.doi.org/10.1111/j.1582-4934.2009.00743.x