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Regulations of Gene Expression in Medullary Thymic Epithelial Cells Required for Preventing the Onset of Autoimmune Diseases

Elimination of potential self-reactive T cells in the thymus is crucial for preventing the onset of autoimmune diseases. Epithelial cell subsets localized in thymic medulla [medullary thymic epithelial cells (mTECs)] contribute to this process by supplying a wide range of self-antigens that are othe...

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Detalles Bibliográficos
Autores principales: Akiyama, Taishin, Shinzawa, Miho, Qin, Junwen, Akiyama, Nobuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3752772/
https://www.ncbi.nlm.nih.gov/pubmed/23986760
http://dx.doi.org/10.3389/fimmu.2013.00249