Genetic modulation of the iris transillumination defect: a systems genetics analysis using the expanded family of BXD glaucoma strains

We investigated the contributions of Tyrp1 and Gpnmb to the iris transillumination defect (TID) in five age cohorts of BXD mice. Using systems genetics, we also evaluated the role of other known pigmentation genes (PGs). Mapping studies indicate that Tyrp1 contributes to the phenotype at all ages, y...

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Detalles Bibliográficos
Autores principales: Swaminathan, Shankar, Lu, Hong, Williams, Robert W, Lu, Lu, Jablonski, Monica M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3752936/
https://www.ncbi.nlm.nih.gov/pubmed/23582180
http://dx.doi.org/10.1111/pcmr.12106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3752936/
https://www.ncbi.nlm.nih.gov/pubmed/23582180
http://dx.doi.org/10.1111/pcmr.12106

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