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Resveratrol Stimulates Sphingosine-1-Phosphate Signaling of Cathelicidin Production

We recently discovered a regulatory mechanism that stimulates production of the multifunctional antimicrobial peptide, cathelicidin antimicrobial peptide (CAMP). In response to subtoxic levels of ER stress, increased sphingosine-1-phosphate (S1P) production activates an NFκB→C/EBPα dependent pathway...

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Detalles Bibliográficos
Autores principales: Park, Kyungho, Elias, Peter M., Hupe, Melanie, Borkowski, Andrew W., Gallo, Richard L., Shin, Kyong-Oh, Lee, Yong-Moon, Holleran, Walter M., Uchida, Yoshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753186/
https://www.ncbi.nlm.nih.gov/pubmed/23856934
http://dx.doi.org/10.1038/jid.2013.133