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Studying arrhythmogenic right ventricular dysplasia with patient-specific iPSCs

Cellular reprogramming of somatic cells to patient-specific induced pluripotent stem cells (iPSCs) enables in-vitro modelling of human genetic disorders for pathogenic investigations and therapeutic screens(1–7). However, using iPSC-derived cardiomyocytes (iPSC-CMs) to model an adult-onset heart dis...

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Detalles Bibliográficos
Autores principales: Kim, Changsung, Wong, Johnson, Wen, Jianyan, Wang, Shirong, Wang, Cheng, Spiering, Sean, Kan, Natalia G., Forcales, Sonia, Puri, Pier Lorenzo, Leone, Teresa C., Marine, Joseph E., Calkins, Hugh, Kelly, Daniel P., Judge, Daniel P., Chen, Huei-Sheng Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753229/
https://www.ncbi.nlm.nih.gov/pubmed/23354045
http://dx.doi.org/10.1038/nature11799