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High Yield Production of a Soluble Human Interleukin-3 Variant from E. coli with Wild-Type Bioactivity and Improved Radiolabeling Properties
Human interleukin-3 (hIL-3) is a polypeptide growth factor that regulates the proliferation, differentiation, survival and function of hematopoietic progenitors and many mature blood cell lineages. Although recombinant hIL-3 is a widely used laboratory reagent in hematology, standard methods for its...
Autores principales: | Hercus, Timothy R., Barry, Emma F., Dottore, Mara, McClure, Barbara J., Webb, Andrew I., Lopez, Angel F., Young, Ian G., Murphy, James M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753260/ https://www.ncbi.nlm.nih.gov/pubmed/23991218 http://dx.doi.org/10.1371/journal.pone.0074376 |
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